Thanks for that Buster, I might give it a try.Buster121 wrote: ↑Thu Feb 27, 2025 1:14 pm Here you go Trev this may help
Foods, Materials, Technologies and Risks
Encyclopedia of Food Safety
Reference work2014, Encyclopedia of Food Safety
A. AnadónMR Martínez-Larrañaga
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Amprolium
Amprolium is structurally similar to vitamin B1. When it is administered orally to chickens, it has a low bioavailability, but the absorbed fraction is widely distributed into the tissues and rapidly eliminated in the urine and feces. Amprolium administered to laying hens is deposited primarily in the egg yolk, and residues can be detected in eggs for 10 days or more after cessation of treatment, depending on the dose and assay sensitivity.
No MRL has been established for this compound.
Chapter
Antiprotozoal Drugs
Greene's Infectious Diseases of the Dog and Cat (Fifth Edition)
Book2021, Greene's Infectious Diseases of the Dog and Cat (Fifth Edition)
Jane E. Sykes, Mark G. Papich
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Amprolium
Amprolium is a thiamine analogue that is used to prevent and treat intestinal coccidiosis (Table 12.1). It is available as a feed additive for livestock and is sometimes administered in food or drinking water to puppies and kittens. To administer to dogs and cats, it is available as a 9.6% (9.6 g/100 mL) oral solution or a soluble powder in a 22.6 g packet, which then must be mixed with food. For treatment of coccidiosis, 1.25 g of 20% amprolium powder can be added to food or 30 mL of 9.6% amprolium solution to 3.8 L of drinking water for 7 days.
Adverse effects of anorexia or diarrhea are rare and primarily occur at high doses and with prolonged use. Central nervous system (CNS) signs can result from thiamine deficiency, which is reversible on addition of thiamine to the diet. However, thiamine supplementation may interfere with the drug’s efficacy.
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No Neil I haven't, we did use something very similar with our cattle during times of extreme stress/sickness, especially calves still on milk.
The only older products I still keep in my loft, which our Dad swore by, are Old hands one eye cold capsules and Old Hand White Sesqui going light tablets. I know plenty will laugh at that, and to be honest I couldn't categorically say wether they work or not. I can say though, that over my 50 years, and our Dad's before, that most birds treated with them did recover, but who's to say that they wouldn't have done anyway !!!
Thankfully I've not had a case of one eye cold for many years now.
That’s all that matters Trev I do things people knock me for but it seems ok for meTrev wrote: ↑Fri Feb 28, 2025 3:10 pmNo Neil I haven't, we did use something very similar with our cattle during times of extreme stress/sickness, especially calves still on milk.
The only older products I still keep in my loft, which our Dad swore by, are Old hands one eye cold capsules and Old Hand White Sesqui going light tablets. I know plenty will laugh at that, and to be honest I couldn't categorically say wether they work or not. I can say though, that over my 50 years, and our Dad's before, that most birds treated with them did recover, but who's to say that they wouldn't have done anyway !!!
Thankfully I've not had a case of one eye cold for many years now.
Interesting about one eye cold that use to be massive when I raced before now you don’t hear of it